The role of sperm DNA fragmentation index (DFI) in investigating fertility, embryonic development,and pregnancy is of academic interest. However, there is ongoing controversy regarding the impactof DFI on pregnancy outcomes and the safety of offspring in the context of Assisted ReproductiveTechnology (ART). Sperm DFI has an impact on both miscarriage rates and birth weight in...Read More
Are the prospective reproductive outcomes in RPL couples related to sperm DNA fragmentation index (DFI) measured by SCSA, morphology and concentration at referral? Design A prospective cohort study including 95 couples seen between 01/04/2018 and 01/12/2019 at the tertiary Copenhagen RPL Unit, Copenhagen University Hospital, Rigshospitalet and Hvidovre Hospital, Denmark. The couples had experienced three...Read More
💃🕺 Check out this lively video featuring some groovy sperm breaking it down.Science meets rhythm in the most unexpected ways! 🎉 . Hey! If you found this post interesting or useful, you can help us get even better by subscribing to our newsletter. Just write your email and you’ll have the latest fertility news. Thank...Read More
Sperm selection of the most competent sperm is a promising way to enhance reproductive outcomes. Apoptosis is the programmed cell death process to maintain tissue homeostasis, and MACS sperm selection of non-apoptotic cells enables the removal of apoptotic sperm from an ejaculate, thus leaving the non-apoptotic available to be microinjected, but given the associated costs...Read More
Historically, only women’s drinking was considered a risk during pregnancy, but new research points to the role of fathers’ habits as well. Men drink more, are more likely to binge drink and are almost four times more likely to develop alcohol use disorder than women, according to the Centers for Disease Control and Prevention. Research clearly shows...Read More
Exposure of the female reproductive tract to either seminal plasma or fluid component of the ejaculate is beneficial to achieving successful embryo implantation and normal embryo development. But whether the “physical” component of sexual intercourse during the peri-transfer period have any influence on frozen-thawed embryo transfer (FET) pregnancy outcomes is not clear. We conducted a...Read More
High childhood BMI is strongly associated with obesity and cardiometabolic disease and mortality in adulthood. Children conceived after FET have a higher risk of being born large for gestational age (LGA) than children conceived after NC. It is well-documented that being born LGA is associated with an increased risk of obesity in childhood, and it...Read More
The integration of artificial intelligence (AI) and deep learning algorithms into medical care has been the focus of development over the last decade, particularly in the field of assisted reproductive technologies and in vitro fertilization (IVF). With embryo morphology the cornerstone of clinical decision making for IVF, the field of IVF is highly reliant on...Read More
In a recent Fertility and Sterility review, researchers summarize the available evidence on the application of artificial intelligence (AI) and machine learning in sperm selection. The success rates of ART have remained relatively low globally due to the lack of proper sperm selection. Despite technological advancements, the final sperm selection is primarily performed manually by an embryologist following...Read More
The development of assisted reproductive technology has allowed offspring in infertile couples, and specifically, allowed infertile men to conceive through Intracytoplasmic Sperm Injection (ICSI). Despite the proven efficacy of In Vitro Fertilisation (IVF) and ICSI, many factors can influence its success. In this review we present an analysis on the effect of Female age, Ovarian...Read More
Sperm Tracer is a unique AI technological software that supports fertility experts and embryologists to evaluate, in real-time, the best sperm for ICSI procedures.
Each embryo carries 50% of the genetic information of an oocyte and 50% of a sperm. Every single sperm participating with 50% of the DNA cargo of the embryo, could play a detrimental role for the embryo itself and its quality.
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