Purpose To create a novel medium that retained human sperm quality following cryopreservation at a higher level than that seen with currently available commercial cryoprotectants. Methods Cryopreservation was achieved via 1:1 dilution with cryoprotectant followed by slow-programmed freezing. A NaCl-free cryopreservation carrier medium based on the use of histidine as the major osmolyte was designed...Read More
To evaluate differences in post-insemination events between fresh and frozen-derived gametes when testicular sperm extraction (TESE) is used. Method A retrospective cohort study including 980 oocytes retrieved across 72 cycles from 30 couples, between January 2017 and September 2023. Gamete sources were fresh (fresh-TESE) or frozen-thawed-TESE (frozen-TESE) from the same patients with non-obstructive azoospermia (NOA),...Read More
Assisted reproductive technology (ART) has emerged as a pivotal solution for human infertility, with intracytoplasmic sperm injection (ICSI) being widely adopted. The quality of sperm is critical to the outcomes of ART, and the selection of optimal sperm is essential for enhancing embryo quality. In recent years, researchers have developed various advanced sperm selection methods...Read More
Are physical activity and sedentary time associated with the DNA fragmentation index (DFI) score and conventional semen parameters in healthy Japanese men? The study found that igher total physical activity was associated with a lower DFI score (P-value for trend = 0.002), with the third and fourth total physical activity quartiles showing a 21% (95% CI 5–34%, P = 0.013)...Read More
Recurrent pregnancy loss (RPL) is a condition affecting up to 5% of couples. We conducted a systematic review and meta-analysis (SRMA) to synthesize the evidence on the relationship between seminal oxidative stress (OS) and RPL. This study aimed to evaluate whether seminal OS markers differ between men from couples experiencing RPL and those from fertile...Read More
The Sperm Tracer
Sperm Tracer is a unique AI technological software that supports fertility experts and embryologists to evaluate, in real-time, the best sperm for ICSI procedures.
Each embryo carries 50% of the genetic information of an oocyte and 50% of a sperm. Every single sperm participating with 50% of the DNA cargo of the embryo, could play a detrimental role for the embryo itself and its quality.
If you believe you are among the pioneers, we may be able to help you reach even higher.
Recent Comments