Are physical activity and sedentary time associated with the DNA fragmentation index (DFI) score and conventional semen parameters in healthy Japanese men?
The study found that igher total physical activity was associated with a lower DFI score (P-value for trend = 0.002), with the third and fourth total physical activity quartiles showing a 21% (95% CI 5–34%, P = 0.013) and a 29% (95% CI 12–43%, P = 0.002) reduction in DFI score compared with the first quartile reference, respectively. There was a trend for a shorter sedentary time to be associated with a lower DFI score, but this failed to reach significance (P-value for trend = 0.057). The first sedentary time quartile showed a 22% reduction in DFI score compared with the fourth quartile reference (95% CI 3–37%, P = 0.024). There were no significant associations between total physical activity, sedentary time and conventional semen parameters.
Conclusions
Higher physical activity and shorter sedentary time are associated with a lower DFI score in Japanese men. However, these associations were not observed with conventional semen parameters.
https://link.springer.com/content/pdf/10.1007/s10815-024-03030-y.pdf
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