In animals, mature sperm are stored in males before ejaculation and sometimes in females before fertilization. Sperm storage provides evolutionary advantages; however, storage can also cause sperm deterioration owing to post-meiotic sperm senescence (PMSS). Yet,...
One-third of infertile couples struggle to conceive despite normal examination and tests. For men, semen analysis is the only widely-adopted diagnostic tool to assess male infertility. However, it is unable to detect abnormal sperm function...
Segregation distortion, the disproportionate inheritance of selfish genetic elements, is an important evolutionary force. While many species carry distorters, it is not clear if humans do. Major limitations for detecting human distortion are the small...
The mammalian spermatozoon neck is a unique structure that functions during spermatid differentiation and spermatozoa swimming, and its contents are critical for post-fertilization embryogenesis. Mutations in proteins localizing to the neck connecting piece (the modified...
To evaluate differences in post-insemination events between fresh and frozen-derived gametes when testicular sperm extraction (TESE) is used. Method A retrospective cohort study including 980 oocytes retrieved across 72 cycles from 30 couples, between January...
Sperm Tracer is a unique AI technological software that supports fertility experts and embryologists to evaluate, in real-time, the best sperm for ICSI procedures.
Each embryo carries 50% of the genetic information of an oocyte and 50% of a sperm. Every single sperm participating with 50% of the DNA cargo of the embryo, could play a detrimental role for the embryo itself and its quality.
If you believe you are among the pioneers, we may be able to help you reach even higher.
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