Sperm provides half of the DNA required to fertilize an egg. If the DNA in sperm is damaged, it may be unable to fertilize the egg, or if fertilization occurs, the resulting embryo may fail to progress normally or properly implant into the uterine lining. Sperm DNA fragmentation index (DFI) is a measurement used to determine the amount of sperm that have abnormal genetic material and has been becoming widely used in clinic. A DFI above 30% is related to infertility and above 20% is regarded to be suboptimal.
Sperm analysis has been revolutionized in recent year. With the fast development of AI system applied in the reproduction felid, it is predicted that AI could play an important role for the development of innovative detection and screening methods.
