One-third of infertile couples struggle to conceive despite normal examination and tests. For men, semen analysis is the only widely-adopted diagnostic tool to assess male infertility.
However, it is unable to detect abnormal sperm function or accurately predict pregnancy except in cases of complete absence of sperm. Sperm function tests (SFT) could help by directing treatment to intracytoplasmic sperm injection where indicated, improving treatment efficiency and reducing overall cost. However, SFT are not currently routinely used in clinical practice.
https://link.springer.com/content/pdf/10.1186/s13561-026-00749-5_reference.pdf
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