The objective of this study was to evaluate the impact of basic semen analysis parameters, assessed according to WHO-2021 criteria, as well as paternal BMI and paternal age on embryological and clinical ICSI outcomes among couples undergoing preimplantation genetic testing for aneuploidy (PGT-A). Our main goal is to provide IVF professionals with information about the impact of these male factors on ICSI outcomes, thus allowing better counseling and informed decision-making.
3101 couples undergoing 4013 intracytoplasmic sperm injection (ICSI) + PGT-A cycles with own-oocytes (years 2013–2021).
This comprehensive analysis provides IVF professionals with useful figures to counsel infertile couples about their chances of success, taking into account the impact of semen characteristics and paternal BMI and age. These estimates are valuable for personalized decision-making about the most effective reproductive strategies to adopt, especially not underestimating male factor, by improving sperm concentration and motility whenever possible before assisted reproductive technologies.
https://link.springer.com/content/pdf/10.1007/s10815-024-03030-y.pdf
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