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IVF
Are the prospective reproductive outcomes in RPL couples related to sperm DNA fragmentation index (DFI) measured by SCSA, morphology and concentration at referral? Design A prospective cohort study including 95 couples seen between 01/04/2018 and 01/12/2019 at the tertiary Copenhagen RPL Unit, Copenhagen University Hospital, Rigshospitalet and Hvidovre Hospital, Denmark. The couples had experienced three...
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Exposure of the female reproductive tract to either seminal plasma or fluid component of the ejaculate is beneficial to achieving successful embryo implantation and normal embryo development. But whether the “physical” component of sexual intercourse during the peri-transfer period have any influence on frozen-thawed embryo transfer (FET) pregnancy outcomes is not clear. We conducted a...
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High childhood BMI is strongly associated with obesity and cardiometabolic disease and mortality in adulthood. Children conceived after FET have a higher risk of being born large for gestational age (LGA) than children conceived after NC. It is well-documented that being born LGA is associated with an increased risk of obesity in childhood, and it...
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The integration of artificial intelligence (AI) and deep learning algorithms into medical care has been the focus of development over the last decade, particularly in the field of assisted reproductive technologies and in vitro fertilization (IVF). With embryo morphology the cornerstone of clinical decision making for IVF, the field of IVF is highly reliant on...
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In a recent Fertility and Sterility review, researchers summarize the available evidence on the application of artificial intelligence (AI) and machine learning in sperm selection. The success rates of ART have remained relatively low globally due to the lack of proper sperm selection. Despite technological advancements, the final sperm selection is primarily performed manually by an embryologist following...
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The development of assisted reproductive technology has allowed offspring in infertile couples, and specifically, allowed infertile men to conceive through Intracytoplasmic Sperm Injection (ICSI). Despite the proven efficacy of In Vitro Fertilisation (IVF) and ICSI, many factors can influence its success. In this review we present an analysis on the effect of Female age, Ovarian...
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Several studies show reductions in some seminal parameters in aged men and describe them as a consequence of many age-dependent changes in male organisms. This study aims to evaluate the impact of age on seminal parameters, particularly the DNA fragmentation index (DFI), and outcomes after in vitro fertilization (IVF) cycles.  https://pubmed.ncbi.nlm.nih.gov/36897559/
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The new year brings hope for new beginnings, perhaps the most pertinent of which is new life. For decades, in-vitro fertilization (IVF) has offered those unable to conceive naturally the chance to have biological children; however, global success rates are notoriously low. Artificial intelligence (AI) is being used to improve the success rates of IVF,...
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The Future Is Coming: Artificial Intelligence in the Treatment of Infertility Could Improve Assisted Reproduction Outcomes—The Value of Regulatory Frameworks. Infertility is a global health issue affecting women and men of reproductive age with increasing incidence worldwide, in part due to greater awareness and better diagnosis. Assisted reproduction technologies (ART) are considered the ultimate step...
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Is it possible to automate the way sperm is injected in an oocyte and improve ICSI consistency between embryologists? The combination of multidisciplinary teams allows the development of automated processes that can reduce variability in certain IVF procedures, while supervised and assisted by experienced embryologists. It is expected that other laboratory procedures can be automated...
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The Sperm Tracer

Sperm Tracer is a unique AI technological software that supports fertility experts and embryologists to evaluate, in real-time, the best sperm for ICSI procedures.

Each embryo carries 50% of the genetic information of an oocyte and 50% of a sperm. Every single sperm participating with 50% of the DNA cargo of the embryo, could play a detrimental role for the embryo itself and its quality.

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